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Generally, the redder the tomato, the more lycopene it has ( Tomato products such as ketchup, tomato juice, tomato paste, and tomato sauces are the richest dietary sources of lycopene in the Western diet, providing over 80% of dietary lycopene in the United States ( Gram for gram, the amount of lycopene in processed tomato products is often much higher than in fresh tomatoes ( For example, ketchup boasts 1014 mg of lycopene per 3.5 ounces (100 grams), while one small, fresh tomato (100 grams) holds only 18 mg (24)

Hypersensitivity reactions may manifest in various ways, ranging from local injection site reactions such as erythema, swelling, and pruritus to more severe systemic reactions including angioedema, anaphylaxis, or generalized urticaria

Patients with a history of megaloblastic anemia should use methylcobalamin formulations rather than cyanocobalamin-containing versions